Table 3 Characteristics of p16/Ki-67 dual staining in suspicious and positive recordings
p16/Ki-67 staining characteristics | p16/Ki-67 result | p-value | ||||
|---|---|---|---|---|---|---|
positive | suspicious | |||||
N | % | N | % | |||
Number of stained cells | 1 | 57 | 16.1 | 36 | 45.0 | 0.000 |
2 | 31 | 8.8 | 18 | 22.5 | ||
3 | 37 | 10.5 | 13 | 16.3 | ||
4 | 17 | 4.8 | 5 | 6.3 | ||
5 | 211 | 59.8 | 8 | 10.0 | ||
p16 staining intensity | appropriate | 238 | 82.6 | 35 | 63.6 | 0.001 |
weak | 50 | 17.4 | 20 | 36.4 | ||
Ki-67 staining intensity | appropriate | 273 | 94.8 | 53 | 96.4 | 1.000 |
weak | 15 | 5.2 | 2 | 3.6 | ||
Cell morphology | preserved | 285 | 99.3 | 51 | 92.7 | 0.007 |
less preserved | 2 | 0.7 | 4 | 7.3 | ||
Counter stain | appropriate | 284 | 99.0 | 52 | 94.5 | 0.055 |
weak | 3 | 1.0 | 3 | 5.5 | ||
Background staining | not present/ weak | 252 | 88.1 | 43 | 78.2 | 0.048 |
strong | 34 | 11.9 | 12 | 21.8 | ||