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Table 2 The results of eleven selected miRNAs analyzed by RT-qPCR

From: Serum expression of selected miRNAs in patients with laryngeal squamous cell carcinoma (LSCC)

miRNA serum

Group

N

Mean+/−SD

p

miR-31

neoplastic

66

0,345 ± 0,090

<  0,001

control

100

0,078 ± 0,036

miR-141

neoplastic

66

0,289 ± 0,079

<  0,001

control

100

0,077 ± 0,082

miR-149a

neoplastic

66

0,168 ± 0,051

0,003

control

100

0,120 ± 0,028

miR-182

neoplastic

66

0,247 ± 0,091

<  0,001

control

100

0,085 ± 0,076

miR-145

neoplastic

66

0,031 ± 0,017

<  0,001

control

100

0,146 ± 0,124

miR-223

neoplastic

66

0,038 ± 0,032

<  0,001

control

100

0,102 ± 0,035

LET-7a

neoplastic

66

0,298 ± 0,110

<  0,001

control

100

0,073 ± 0,034

miR-133a

neoplastic

66

0,058 ± 0,024

0,007

control

100

0,204 ± 0,156

miR-485-3p

neoplastic

66

0,394 ± 0,111

<  0,001

control

100

0,136 ± 0,078

miR-122

neoplastic

66

0,497 ± 0,202

<  0,001

control

100

0,147 ± 0,058

miR-33

neoplastic

66

1013 ± 0,184

<  0,001

control

100

0,136 ± 0,071

  1. Significantly differentially expressed miRNAs in the serum of LSCC patients (n = 66) when compared to healthy controls (n = 100). Data represent the mean ± S.D