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Fig. 4 | Diagnostic Pathology

Fig. 4

From: IL-17A increases MHC class I expression and promotes T cell activation in papillary thyroid cancer patients with coexistent Hashimoto’s thyroiditis

Fig. 4

IL-17A promotes T cell activation in co-cultures of CD3+CD8+CD25+T cells and PTC cell lines. a, flow cytometry measurements of %CD25+ of CD3+T cells in coculture systems containing CD3+CD8+CD25+T cells (effector cells, E) and pretreated PTC cells (K-1 and TPC-1 treated with 0.1 μg/μL of IL-17A; target cells, T) at various E:T ratio (10:1 and 30:1). (**P < 0.01) b, ELISA results of IL-2 production in coculture systems. (*P < 0.05) c, Elisa results of IFN-γ production in coculture systems at a 30:1 ratio. (***P < 0.001) d, MFI of PD-1 expression in co-culture systems. (*P < 0.05)

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