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Fig. 1 | Diagnostic Pathology

Fig. 1

From: The importance of EGFR mutation testing in squamous cell carcinoma or non-small cell carcinoma favor squamous cell carcinoma diagnosed from small lung biopsies

Fig. 1

A representative case showing moderately differentiated SqCC in bronchoscopic biopsy diagnosed as adenosquamous carcinoma after surgical resection. a Bronchoscopic biopsy specimen displaying classical SqCC morphology with keratin pearl formation. b, c Tumor cells in the biopsy specimen positive for p40 and negative for TTF-1 staining. d Subsequent surgical resection demonstrating a diagnosis of ADSC. e, f The squamous carcinoma component immunoreactive with p40 and non-reactive with TTF-1, while the adenocarcinoma component immunoreactive with TTF-1 and non-reactive with p40. g Real-time PCR analysis of the biopsy specimen positive for EGFR exon 19 deletions

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Diagnostic Pathology

ISSN: 1746-1596

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