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Table 2 Clinicopathological summary for EGFR mutation-positive patients with SqCC or NSCC favor SqCC diagnosed from small biopsies

From: The importance of EGFR mutation testing in squamous cell carcinoma or non-small cell carcinoma favor squamous cell carcinoma diagnosed from small lung biopsies

Patient Age Sex Smoking Status Mutation Histologic subtype ADC marker SqCC marker Additional specimens
1 44 F Never smoker E19D SqCC n.a. n.a. Subsequent LUL lobectomy with diagnosis as ADSC
2 57 F Never smoker E19D SqCC TTF1 (−) CK5/6 (+); diffuse Another RLL biopsy with diagnosis as SqCC
3 59 F Never smoker L858R/T790 M SqCC TTF1 (−) CK5/6 (+); diffuse n.a.
4 51 F Never smoker L858R/T790 M SqCC n.a. n.a. n.a.
5 81 F Smoker E19D NSCC favor SqCC TTF1 (−) p40 (+); diffuse n.a.
6 58 F Never smoker E19D NSCC favor SqCC TTF1 (−) p40 (+); diffuse Subsequent RUL lobectomy with diagnosis as ADSC
7 76 F Never smoker L858R NSCC favor SqCC TTF1 (−) p40 (+); diffuse n.a.
8 63 F Never smoker L858R SqCC TTF1 (−) p40 (+); diffuse n.a.
9 84 F Unknown L858R SqCC TTF1 (−) p40 (+); diffuse n.a.
10 74 F Never smoker L858R SqCC TTF1 (−) p40 (+); diffuse Subsequent RUL lobectomy with diagnosis as ADSC
11 86 M Smoker L858R NSCC favor SqCC TTF1 (−) p40 (+); moderate n.a.
12 81 M Never smoker L858R NSCC favor SqCC TTF1 (−) p40 (+); moderate n.a.
13 81 M Never smoker L858R NSCC favor SqCC TTF1 (−) p40 (+); moderate n.a.
  1. n.a not available