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Table 2 Clinicopathological summary for EGFR mutation-positive patients with SqCC or NSCC favor SqCC diagnosed from small biopsies

From: The importance of EGFR mutation testing in squamous cell carcinoma or non-small cell carcinoma favor squamous cell carcinoma diagnosed from small lung biopsies

Patient

Age

Sex

Smoking Status

Mutation

Histologic subtype

ADC marker

SqCC marker

Additional specimens

1

44

F

Never smoker

E19D

SqCC

n.a.

n.a.

Subsequent LUL lobectomy with diagnosis as ADSC

2

57

F

Never smoker

E19D

SqCC

TTF1 (−)

CK5/6 (+); diffuse

Another RLL biopsy with diagnosis as SqCC

3

59

F

Never smoker

L858R/T790 M

SqCC

TTF1 (−)

CK5/6 (+); diffuse

n.a.

4

51

F

Never smoker

L858R/T790 M

SqCC

n.a.

n.a.

n.a.

5

81

F

Smoker

E19D

NSCC favor SqCC

TTF1 (−)

p40 (+); diffuse

n.a.

6

58

F

Never smoker

E19D

NSCC favor SqCC

TTF1 (−)

p40 (+); diffuse

Subsequent RUL lobectomy with diagnosis as ADSC

7

76

F

Never smoker

L858R

NSCC favor SqCC

TTF1 (−)

p40 (+); diffuse

n.a.

8

63

F

Never smoker

L858R

SqCC

TTF1 (−)

p40 (+); diffuse

n.a.

9

84

F

Unknown

L858R

SqCC

TTF1 (−)

p40 (+); diffuse

n.a.

10

74

F

Never smoker

L858R

SqCC

TTF1 (−)

p40 (+); diffuse

Subsequent RUL lobectomy with diagnosis as ADSC

11

86

M

Smoker

L858R

NSCC favor SqCC

TTF1 (−)

p40 (+); moderate

n.a.

12

81

M

Never smoker

L858R

NSCC favor SqCC

TTF1 (−)

p40 (+); moderate

n.a.

13

81

M

Never smoker

L858R

NSCC favor SqCC

TTF1 (−)

p40 (+); moderate

n.a.

  1. n.a not available