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Table 3 Immunohistochemical and in situ hybridization for both the primary and the metastatic tumors

From: Mesonephric adenocarcinoma of the cervix: a case report with a three-year follow-up, lung metastases, and next-generation sequencing analysis

 

Endocervical Tumor

Lung Tumor

Beta-catenin

NP

+ (membrane stain)

Calretinin

CEAm

NP

CD10

+ (luminal pattern)

+ (luminal pattern)

Cytokeratin AE1/AE3

NP

+

Cytokeratin 7

+

NP

Cytokeratin 20

NP

Estrogen Receptor

Inhibin, alpha

+

p16INK4A

+ (Non-block)

+ (Non-block)

p53

Negative (Wild type)

NP

PAX-2

+

+

PAX-8

NP

+

Progesterone Receptor

NP

TTF-1

NP

+

Vimentin

NP

+

WT-1

+

+

1q

NAa

Gain

  1. a CISH was performed on the available tissue sample form the endocervical tumor. However, the results were not satisfactory and no analysis could be carried out