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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Triple malignancy (NET, GIST and pheochromocytoma) as a first manifestation of neurofibromatosis type-1 in an adult patient

Fig. 2

a Histopathology - pheochromocytoma, tumor with a trabecular pattern of polygonal cells set in rich vascular network. Cells have finely granular cytoplasm, oval nuclei with prominent nucleoli and a coarsely clumped chromatin, without mitotic figures, HE staining, 200x. b Histopathology - pheochromocytoma, diffuse strong positivity of tumor cells, chromogranin, 200x. c Histopathology - pheochromocytoma, diffuse strong positivity of tumor cells, synaptophysin, 200x. d Histopathology - pheochromocytoma, positivity of the sustentacular cells at the periphery of the tumor cell clusters, S100 protein, 200x

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