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Table 2 AMACR and CK20 expression in urothelial carcinoma in situ and non-neoplastic urothelium

From: Does the addition of AMACR to CK20 help to diagnose challenging cases of urothelial carcinoma in situ?

  

Positive

Partial positive

Negative

Mean intensity

CIS with IHC (n = 22)

AMACR

16/22 (73%)

0/22 (0%)

6/22 (27%)

2.4

CK20

21/22 (95%)

0/22 (0%)

1/22 (5%)

3.0

Non-neoplastic with IHC (n = 30)

AMACR

0/30 (0%)

1/30 (3%)

29/30 (97%)

2.0

CK20

5/30 (17%)

1/30 (3%)

24/30 (80%)

2.7

CIS without IHC (n = 20)

AMACR

20/20 (100%)

0/20 (0%)

0/20 (0%)

2.1

  1. CIS, Carcinoma in situ; IHC, Immunohistochemistry