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Table 1 All of the involved markers in esophageal cancer susceptibility among the Iranian patients

From: Genetic and molecular bases of esophageal Cancer among Iranians: an update

Study (et al) Year Gene Purpose Population Results
salehi [9] 2006 eIF4E Prognosis 99 N/Ta Over expression
MOGHBELI [10] 2014 MSI1 Diagnosis 53 N/T Correlation with sex
KAHKHAIE [11] 2014 MUC1 Prognosis 50 N/T Correlation with stage, grade, and lymph node
SEDIGHI [12] 2016 MMP13 Diagnosis and Prognosis 66 patients
54 controls
Correlation with lymph node, tumor size, and survival
golyan [13] 2019 MMP21 Diagnosis and Prognosis 58 N/T Correlation with stage
SALEHI [14] 2016 BRUCE Diagnosis 50 N/T Correlation with stage
ABBASZADEGAN [15] 2008 P16 Diagnosis 52 patients
50 controls
Hypermethylation
taghavi [16] 2010 P16 Diagnosis 50 N/T Hypermethylation
ABBASZADEGAN [17] 2005 P16 Diagnosis 30 patients
30 controls
Hypermethylation
abedi-ardekani [18] 2011 P53 Diagnosis 119 patients Mutation
khalilipour [19] 2018 KCNJ12 Diagnosis 9 patients Mutation
forghanifard [20] 2019 DIDO1 Diagnosis 50 N/T Correlation with depth of invasion
Ghobadi [21] 2018 CDKN2A Prognosis 123 patients Polymorphism was correlated with ESCC risk
hashemi-bidokhti [22] 2017 MAML1 Diagnosis and Prognosis 56 N/T Over expression was correlated with depth of invasion, grade, stage, and sex
forghanifard [23] 2012 MAML1, TWIST1 Diagnosis and Prognosis 55 N/T Over expressions were correlated with lymph node metastasis and stage
MOGHBELI [24] 2013 EGFR, PYGO2 Diagnosis and Prognosis 55 N/T Correlation with stage and grade
FORGHANIFARD [25] 2014 SALL4, SOX2 Diagnosis 50 N/T Correlation with lymph node and depth of invasion
MAHMOUDIAN [26] 2017 Cripto-1 Diagnosis 50 N/T Correlation with tumor grade, stage, and location
MALLAK [27] 2016 EVX1 Diagnosis 50 N/T Correlation with lymph node and depth of invasion
forghanifard [28] 2018 SIZN1 Diagnosis 50 N/T Correlation with depth of invasion and lymph node metastasis
ANSARI [29] 2016 miR-93 Diagnosis 30 N/T Over expression
ANSARI [29] 2016 miR-143 Diagnosis 30 N/T Under expression
GHASEMI [30] 2018 miR-371–373 Diagnosis 36 N/T Over expression
sahebi [31] 2016 Linc-ROR Diagnosis 30 N/T Correlation with grade
maghsudlu [32] 2019 miR-27a Diagnosis and Prognosis 30 N/T Over expression
AKBARI [33] 2008 BRCA2 Diagnosis 197 patients
254 controls
Mutation
forghanifard [34] 2011 MAGE-A4 Diagnosis and Prognosis 41 N/T Over expression
  1. aTumor tissues and normal margins