Skip to main content
Fig. 1 | Diagnostic Pathology

Fig. 1

From: LncRNA DNM3OS promotes proliferation and inhibits apoptosis through modulating IGF1 expression by sponging MiR-126 in CHON-001 cells

Fig. 1

DNM3OS was low-expressed in OA tissues, had negative correlation with miR-126 and promoted CHON-001 cells viability. (a) The expression of lncRNA DNM3OS in human OA tissues was significantly lower, while miR-126 was obviously higher than in normal tissues using RT-qPCR. (b) The expression of DNM3OS was negatively correlated with the miR-126 level in OA samples by Spearman’s correlation analysis. (c) The expression of DNM3OS was negatively correlated with the miR-126 level in normal samples by Spearman’s correlation analysis. (d) The transfection efficiency of DNM3OS was confirmed by RT-qPCR. (e) CHON-001 cells viability was improved or inhibited by DNM3OS or silencing DNM3OS by CCK-8 assay. aP < 0.05 vs. Blank, bP < 0.05 vs. NC, cP < 0.05 vs. DNM3OS, dP < 0.05 vs. siNC. siDNM3OS: small interfering dynamin 3 opposite strand; NC: negative control; OD: optical density

Back to article page

Diagnostic Pathology

ISSN: 1746-1596

Contact us