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Fig. 3 | Diagnostic Pathology

Fig. 3

From: LncRNA DNM3OS promotes proliferation and inhibits apoptosis through modulating IGF1 expression by sponging MiR-126 in CHON-001 cells

Fig. 3

CHON-001 cell migration and invasion were facilitated by the up-regulation DNM3OS, while the knockdown of DNM3OS showed opposite results. (a) CHON-001 cells migration was promoted by DNM3OS, while silencing DNM3OS inhibited cells migration as indicated by wound healing assay. (b) The distance of scratch was quantified. (c) CHON-001 cells invasion was enhanced by DNM3OS, while silencing DNM3OS suppressed cells invasion as indicated by transwell assay. (d) The number of invasion cells was quantified. aP < 0.05 vs. Blank, bP < 0.05 vs. NC, cP < 0.05 vs. DNM3OS, dP < 0.05 vs. siNC. siDNM3OS: small interfering dynamin 3 opposite strand; NC: negative control

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Diagnostic Pathology

ISSN: 1746-1596

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