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Table 1 Clinicopathological and genetic features of ALK-rearranged renal cell carcinoma in 20 cases

From: ALK-TPM3 rearrangement in adult renal cell carcinoma: a case report and literature review

No. Age Sex Size (cm) Furhman Grade pTNM Follow-up Fusion gene Sickle cell trait
Childern young adults (< 20 years old)
 1 [9] 16 M 6.5 ND T1N1M0 A (9 m) VCL yes
 2 [10] 6 M 4.5 ND T1bN0M0 A (21 m) VCL yes
 3 [13] 6 M 3 ND T1aN0M0 A (19 m) VCL yes
 4 [14] 12 F 6 ND ND A (1y) TPM3 no
 5 [15] 16 M 4.5 4 T3aNXMX ND TPM3 no
 6 [16] 16 F 7 4 T3aN1MX ND TPM3 no
 7 [15] 14 M 3.7 4 T1aN1MX ND TPM3 no
 8 [16] 16 M 5.5 3 and 4 T1bN0M0 ND HOOK1 no
Adults (> 20 years old)
 9 [17] 40 F 4.5 ND T1bNxM0 A (15 m) ND no
 10 [18] 55 F 3.1 4 T1aNxM0 A (8 m) TPM3 no
 11 [19] 33 F ND 3 T2aN1M0 A (27y) STRN no
 12 [19] 38 M 4.5 4 T1aN2M1 D (3 m) STRN no
 13 [12] 36 F 4 ND T1aNxM0 A(2y) TPM3 no
 14 [12] 53 F 2.5 ND T1aNxM0 A(3y) EML4 no
 15 [20] 49 M 6.4 ND T1bN1M0 A(24 m) TPM3 no
 16 [20] 52 F 3.5 ND T1aN0M0 A(8 m) EML4 no
 17 [21] 44 M 3 3 T1aNxM0 A(12y) ND no
 18 [11] 61 M 5 2 T1bNxM0 D(4y) ND no
 19 [11] 59 M 5.5 3 T1bNxM0 D(1.4y) ND no
 20 58 M 2 4 T1aN0M0 A(8 m) TPM3 no
  1. ND Not Done, A Alive, D Died