Table 1 Clinicopathological and genetic features of ALK-rearranged renal cell carcinoma in 20 cases
From: ALK-TPM3 rearrangement in adult renal cell carcinoma: a case report and literature review
No. | Age | Sex | Size (cm) | Furhman Grade | pTNM | Follow-up | Fusion gene | Sickle cell trait |
|---|---|---|---|---|---|---|---|---|
Childern young adults (< 20 years old) | ||||||||
1 [9] | 16 | M | 6.5 | ND | T1N1M0 | A (9 m) | VCL | yes |
2 [10] | 6 | M | 4.5 | ND | T1bN0M0 | A (21 m) | VCL | yes |
3 [13] | 6 | M | 3 | ND | T1aN0M0 | A (19 m) | VCL | yes |
4 [14] | 12 | F | 6 | ND | ND | A (1y) | TPM3 | no |
5 [15] | 16 | M | 4.5 | 4 | T3aNXMX | ND | TPM3 | no |
6 [16] | 16 | F | 7 | 4 | T3aN1MX | ND | TPM3 | no |
7 [15] | 14 | M | 3.7 | 4 | T1aN1MX | ND | TPM3 | no |
8 [16] | 16 | M | 5.5 | 3 and 4 | T1bN0M0 | ND | HOOK1 | no |
Adults (> 20 years old) | ||||||||
9 [17] | 40 | F | 4.5 | ND | T1bNxM0 | A (15 m) | ND | no |
10 [18] | 55 | F | 3.1 | 4 | T1aNxM0 | A (8 m) | TPM3 | no |
11 [19] | 33 | F | ND | 3 | T2aN1M0 | A (27y) | STRN | no |
12 [19] | 38 | M | 4.5 | 4 | T1aN2M1 | D (3 m) | STRN | no |
13 [12] | 36 | F | 4 | ND | T1aNxM0 | A(2y) | TPM3 | no |
14 [12] | 53 | F | 2.5 | ND | T1aNxM0 | A(3y) | EML4 | no |
15 [20] | 49 | M | 6.4 | ND | T1bN1M0 | A(24 m) | TPM3 | no |
16 [20] | 52 | F | 3.5 | ND | T1aN0M0 | A(8 m) | EML4 | no |
17 [21] | 44 | M | 3 | 3 | T1aNxM0 | A(12y) | ND | no |
18 [11] | 61 | M | 5 | 2 | T1bNxM0 | D(4y) | ND | no |
19 [11] | 59 | M | 5.5 | 3 | T1bNxM0 | D(1.4y) | ND | no |
20 | 58 | M | 2 | 4 | T1aN0M0 | A(8 m) | TPM3 | no |