Fig. 3

Effects of miR-601 on cell proliferation, migration and invasion in AGS and SGC-7901 cells. a In the two cell lines, expression of miR-601 was significantly increased by miR-601 mimic transfection, while transfection with miR-601 inhibitors resulted in lower expression than the corresponding negative control (** P < 0.01 and *** P < 0.001). b Cell proliferation was enhanced by overexpression of miR-601, but was suppressed by knockdown of miR-601 in both AGS and SGC-7901 cells (*P < 0.05 and ** P < 0.01). c and d Overexpression of miR-601 by miR-601 mimic transfection could promote the cell migration and invasion, but the downregulated miR-601 expression could inhibit the cell migration and invasion (**P < 0.01 and ***P < 0.001)