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Table 1 Expression of CPXM2 and clinicopathological characteristics in osteosarcoma patients

From: Overexpression of carboxypeptidase X M14 family member 2 predicts an unfavorable prognosis and promotes proliferation and migration of osteosarcoma

Item N CPXM2 positive CPXM2 negative P
Tumor tissue 36 21 15 < 0.001*
Noncancerous bone tissue 36 10 26  
Age (years)
  ≤ 19 17 10 7 0.912a
  > 19 19 11 8  
Sex
 Male 21 12 9 0.876a
 Female 15 9 6  
Histologic grade
 I 4 1 3  
 II 7 4 3 < 0.05*
 III 25 16 9  
Histologic subtypes
 Osteoblastic 18 15 3 < 0.01*
 Fibroblastic 4 1 3  
 Chondroblastic 3 1 2  
 Mixed 11 4 7  
Enneking clinical stages
 I-II 14 5 9 < 0.01*
 III 22 16 6  
Response to chemotherapy
 Poor 9 5 4 0.926a
 Good 7 4 3  
 NA (n = 12) 20    
TNM stages
 I- II 14 5 9 < 0.01*
 III-IV 22 16 6  
Pulmonary metastasis
 + 22 17 5 < 0.001*
 - 14 4 10  
History of trauma or bone fracture
 + 11 7 4 0.756
 - 25 14 11  
E-Cadherin
 + 12 4 8 < 0.01*
- 24 17 7  
  1. aStatistical significance was determined with the χ2 test/χ2 Goodness-of-Fit Test
  2. *Statistical significance was found with the Chi-square test/Chi-Square Goodness-of-Fit Test