Fig. 1
From: MicroRNA 3113-5p is a novel marker for early cardiac ischemia/reperfusion injury
Establishment of a murine model bearing cardiac ischemia/reperfusion (I/R) injury. a Electrocardiogram monitoring of mice with (ischemia group) or without (Sham group) coronary artery occlusion. Mice after re-opening of the left anterior descending (LAD) artery (perfusion group) were also subject to ECG monitoring. b ELISA detection of serum cTnI levels in Sham group of mice and in mice with distinct perfusion time. c Hematoxylin & Eosin (HE) staining of heart tissues were performed. Myocardial cells in the sham group were well-ordered with regular structure, while myocardial cells from the I/R injured mice were swelling in the plasma (black arrow) and showed slight interstitial edema (blue arrow) or occasional cell hypertrophy (green arrow) after 3 or 6 h’ reperfusion. *, p < 0.05 vs. Sham