|
Histological subtype
|
PRMT1
|
ZEB1
|
RUNX1
|
TWIST1
|
|---|
|
+
|
–
|
+
|
–
|
+
|
–
|
+
|
–
|
|---|
|
ccRCC
|
73/120 (60.8)
|
47/120 (39.2)
|
37/113 (32.7)
|
76/113 (67.3)
|
70/117 (59.8)
|
47/117 (40.2)
|
112/115 (97.4)
|
3/115 (2.6)
|
|
pRCC I
|
4/7 (57.1)
|
3/7 (42.9)
|
0/7 (0)
|
7/7 (100)
|
2/7 (28.6)
|
5/7 (71.4)
|
7/7 (100)
|
0/7 (0.0)
|
|
pRCC II
|
12/16 (75.0)
|
4/16 (25.0)
|
1/16 (6.6)
|
14/15 (93.4)
|
7/16 (43.8)
|
9/16 (56.3)
|
16/16 (100)
|
0/16 (0.0)
|
|
chRCC
|
12/28 (42.8)
|
16/28 (57.2)
|
2/27 (7.1)
|
25/27 (92.9)
|
13/28 (46.4)
|
15/28 (53.6)
|
28/28 (100)
|
0/28 (0.0)
|
|
RO
|
24/25 (96.1)
|
1/25 (9.4)
|
24/25 (96.0)
|
1/25 (4.0)
|
9/25 (36.0)
|
16/25 (64.0)
|
25/25 (100)
|
0/25 (0.0)
|
|
CDC
|
5/7 (71.4)
|
2/7 (28.6)
|
3/7 (42.9)
|
4/7 (57.1)
|
3/7 (42.9)
|
4/7 (57.1)
|
7/7 (100)
|
0/7 (0.0)
|
|
MLCRN-LMP
|
5/5 (100)
|
0/0 (0.0)
|
0/5 (0)
|
5/5 (100)
|
5/5 (100)
|
0/5 (0.0)
|
5/5 (100)
|
0/5 (0.0)
|
|
P value
|
0.044*
|
<0.001*
|
0.149
|
0.897
|
- Abbreviations: PRMT1, protein arginine methyltransferase 1; ZEB1, Zinc Finger E-Box Binding Homeobox 1; RUNX1, Runt-related transcription factor 1; TWIST1, Twist Family BHLH Transcription Factor 1; ccRCC, clear cell renal cell carcinomas; pRCC I, papillary renal cell carcinoma type I; pRCC II, papillary renal cell carcinoma type I; chRCC, chromophobe renal cell carcinoma;CDC, collecting duct carcinomas-Bellini; MLCRN-LMP, multilocular cystic renal neoplasm of low malignant potential; +, positive; −, negative
- *Statistically significant p-value
