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Table 3 Evaluation of co-expression patterns of PRMT1 and other transcription factors ZEB1, RUNX1, and TWIST1 in ccRCC

From: PRMT1 expression in renal cell tumors- application in differential diagnosis and prognostic relevance

IHC marker (total cases)

PRMT1

P value

positive

negative

ZEB1 (113)

 positive

27 (40.9)

10 (21.3)

0.028*

 negative

39 (59.1)

37 (78.7)

RUNX1 (117)

 positive

48 (68.6)

22 (46.8)

0.019*

 negative

22 (31.4)

25 (53.2)

TWIST1 (115)

 nuclear ± cytoplasmic

37 (53.6)

10 (21.7)

<0.001*

 cytoplasmic

32 (46.4)

36 (78.3)

  1. Abbreviations: PRMT1, protein arginine methyltransferase 1; ZEB1, Zinc Finger E-Box Binding Homeobox 1; RUNX1, Runt-related transcription factor 1; TWIST1, Twist Family BHLH Transcription Factor 1; ccRCC, clear cell renal cell carcinomas
  2. *Statistically significant p-value