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Table 6 Immunohistochemical heterogeneity of PRMT1 in ccRCC with different nuclear grade and stage

From: PRMT1 expression in renal cell tumors- application in differential diagnosis and prognostic relevance

  PRMT1 p-value
  homogenous positive heterogeneous homogenous negative  
Grade
 I/II 22 (24.5) 40 (44.4) 28 (31.1) 0.017*
 III/IV 2 (6.5) 11 (35.5) 18 (58.0)  
Stage
 pT1/pT2 19 (26.8) 30 (42.3) 22 (31.0) 0.040*
 pT3/pT4 5 (10.2) 20 (40.8) 24 (49.0)  
  1. Abbreviation: PRMT1, protein arginine methyltransferase 1
  2. ISUP (International Society of Urological Pathology) nuclear grading system and updated American Joint Committee on Cancer (AJCC) tumor–node–metastasis (TNM) classification 8th edition for tumor staging were used. *Statistically significant p-value