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Table 6 Immunohistochemical heterogeneity of PRMT1 in ccRCC with different nuclear grade and stage

From: PRMT1 expression in renal cell tumors- application in differential diagnosis and prognostic relevance

 

PRMT1

p-value

 

homogenous positive

heterogeneous

homogenous negative

 

Grade

 I/II

22 (24.5)

40 (44.4)

28 (31.1)

0.017*

 III/IV

2 (6.5)

11 (35.5)

18 (58.0)

 

Stage

 pT1/pT2

19 (26.8)

30 (42.3)

22 (31.0)

0.040*

 pT3/pT4

5 (10.2)

20 (40.8)

24 (49.0)

 
  1. Abbreviation: PRMT1, protein arginine methyltransferase 1
  2. ISUP (International Society of Urological Pathology) nuclear grading system and updated American Joint Committee on Cancer (AJCC) tumor–node–metastasis (TNM) classification 8th edition for tumor staging were used. *Statistically significant p-value
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Diagnostic Pathology

ISSN: 1746-1596

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