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Table 2 Univariate and multivariate Cox proportional hazard regression models predicting overall survival

From: The role of p-Stat3 Y705 immunohistochemistry in glioblastoma prognosis

  Univariable Multivariable
HR (95% CI) p-value HR (95% CI) p-value
Age (years) 1.02 (1–1.05) 0.039 1.04 (1.01–1.06) 0.01
p-Stat3 percentage ≥ 20% 4.86 (2.91–8.11) <  0.001 5.69 (3.27–9.91) <  0.001
Frontal 0.84 (0.55–1.28) 0.419 1.02 (0.61–1.71) 0.945
Parietal 0.86 (0.52–1.41) 0.555 0.6 (0.35–1.04) 0.068
Temporal 0.94 (0.59–1.49) 0.799 0.84 (0.5–1.42) 0.522
Occipital 0.81 (0.44–1.5) 0.511 0.81 (0.4–1.64) 0.562
Brainstem 1.24 (0.3–5.07) 0.764 2.91 (0.62–13.75) 0.177
  1. The multivariate model includes all the variables in the table
  2. A second model was created adding to these variables, gender, as well as tumour volume (cm3), where we found HR p-Stat3 percentage ≥ 20% = 4.86 (95% CI 2.91–8.11), p <  0.001
  3. HR Hazard ratio, CI Confidence interval