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Table 2 Univariate and multivariate Cox proportional hazard regression models predicting overall survival

From: The role of p-Stat3 Y705 immunohistochemistry in glioblastoma prognosis

 

Univariable

Multivariable

HR

(95% CI)

p-value

HR

(95% CI)

p-value

Age (years)

1.02

(1–1.05)

0.039

1.04

(1.01–1.06)

0.01

p-Stat3 percentage ≥ 20%

4.86

(2.91–8.11)

<  0.001

5.69

(3.27–9.91)

<  0.001

Frontal

0.84

(0.55–1.28)

0.419

1.02

(0.61–1.71)

0.945

Parietal

0.86

(0.52–1.41)

0.555

0.6

(0.35–1.04)

0.068

Temporal

0.94

(0.59–1.49)

0.799

0.84

(0.5–1.42)

0.522

Occipital

0.81

(0.44–1.5)

0.511

0.81

(0.4–1.64)

0.562

Brainstem

1.24

(0.3–5.07)

0.764

2.91

(0.62–13.75)

0.177

  1. The multivariate model includes all the variables in the table
  2. A second model was created adding to these variables, gender, as well as tumour volume (cm3), where we found HR p-Stat3 percentage ≥ 20% = 4.86 (95% CI 2.91–8.11), p <  0.001
  3. HR Hazard ratio, CI Confidence interval