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Table 3 Multivariate Cox proportional hazard regression models predicting overall survival, for p-Stat3 percentage adjusting for different confounders

From: The role of p-Stat3 Y705 immunohistochemistry in glioblastoma prognosis

Models HR (95% CI) P-value
Model 1 5.69 (3.27–9.91) <  0.001
Model 2 4.86 CI 2.91–8.11 <  0.001
Model 3 7.8 (2.88–21.11) < 0.001
  1. Model 1 - multivariate Cox proportional hazard regression model including age (years), Stat3 percentage > = 20%, localizations (frontal, parietal, temporal, occipital, brainstem)
  2. Model 2 – model 1 plus gender and tumour volume (cm3)
  3. Model 3 – model 2 plus necrosis (μm2)
  4. HR Hazard ratio, CI Confidence interval