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Table 3 Multivariate Cox proportional hazard regression models predicting overall survival, for p-Stat3 percentage adjusting for different confounders

From: The role of p-Stat3 Y705 immunohistochemistry in glioblastoma prognosis

Models

HR

(95% CI)

P-value

Model 1

5.69

(3.27–9.91)

<  0.001

Model 2

4.86

CI 2.91–8.11

<  0.001

Model 3

7.8

(2.88–21.11)

< 0.001

  1. Model 1 - multivariate Cox proportional hazard regression model including age (years), Stat3 percentage > = 20%, localizations (frontal, parietal, temporal, occipital, brainstem)
  2. Model 2 – model 1 plus gender and tumour volume (cm3)
  3. Model 3 – model 2 plus necrosis (μm2)
  4. HR Hazard ratio, CI Confidence interval
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Diagnostic Pathology

ISSN: 1746-1596

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