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Table 1 Clinical and histopathological charateristics of the two patients with SRC-FTC

From: Signet ring cell variant of follicular thyroid carcinoma: Report of two cases with focus on morphological, expressional and genetic characteristics

          

Immunohistochemical markers

Case no.

Gender

Age at surgery

FNA diagnosis

Histo-pathological diagnosis

SRC component (%)

Vascular or capsular invasion

Tumor size (mm)

ETE

pTNM v8

TTF1

THYR

PAX8

CDX2

PDX1

Ki-67%

1

M

71

Bethesda IV

miFTC

> 50

Capsular

38

No

pT2Nx

+

+

+

4

2

M

51

Bethesda III

miFTC

30–50

Capsular

22

No

pT2Nx

+

+

+

1.9

  1. SCR-FTC; follicular thyroid carcinoma with signet ring cell morphology
  2. M male, FNA fine needle aspiration biopsy, miFTC minimally invasive follicular thyroid carcinoma
  3. ETE extrathyroidal extension