Skip to main content
Fig. 1 | Diagnostic Pathology

Fig. 1

From: Aberrant expression of miR-214 is associated with obesity-induced insulin resistance as a biomarker and therapeutic

Fig. 1

miR-214 served a regulator of DPP4 in adipocytes. a. The 3′-UTR of DPP4 had complementary sequence of miR-214. b. Expression of miR-214 in adipocytes was upregulated by miR-214 mimic, but was downregulated by miR-214 inhibitor. c. Relative luciferase activity of the wild-type 3′-UTR of DPP4 was significantly suppressed by the overexpression of miR-214, but was promoted by the knockdown of miR-214. d and e. Effect of miR-214 on the mRNA d and protein e expression of DPP4. *P < 0.05 and **P < 0.01

Back to article page