Fig. 2

Macroscopic and microscopic findings. (a) Macroscopic findings. The solid tumor (3.5 × 2.7 × 2.5 cm) was encapsulated by spleen parenchyma, and the cut surface was a yellowish white. (b, c) Microscopic findings on hematoxylin and eosin (HE) staining. Each lobular lesion was surrounded by fibrous tissue and filled with blood cells (B HE × 40, C HE× 100). (d) The lesions consist of many vascular channels (HE × 100). Immunohistochemical findings of the lesion. (e) Negativity of capillaries and small veins for CD8 (× 100) and (f) positivity for CD31 (× 100). Only lymphocytes were positive for CD8 (e). (g) Positivity of capillaries for CD34 (× 100). (h) Some tumor cells were positive for IGF-II (× 400). Bar scale, 100 μm. (b-h)