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Table 2 Number and percentage of cases meeting each diagnostic criterion of Gerami and Gaiser for dysplastic nevi and early-stage acral and cutaneous melanomas

From: Four-color fluorescence in-situ hybridization is useful to assist to distinguish early stage acral and cutaneous melanomas from dysplastic junctional or compound nevus

 

DN, n(%)

melanoma, n(%)

Total, n

50

59

Gerami’s criteria

 RREB1 > CEP6 (> 55%)

0

9 (15.3)

 RREB1 > 2 (> 29%)

3 (6.0)

44 (74.6)

 MYB<CEP6 (> 40%)

1 (2.0)

24 (40.7)

 CCND1 > 2 (> 38%)

3 (6.0)

54 (91.5)

 FISH positive

3 (6.0)

56 (94.9)

Gaiser’s criteria

 RREB1 aberrant (> 63%)

3 (6.0)

28 (47.5)

 MYB<CEP6 (> 31%)

1 (2.0)

30 (50.8)

 MYB ≥ 2.5

3 (6.0)

28 (47.5)

 CCND1 ≥ 2.5

3 (6.0)

52 (88.1)

 FISH positive

5 (10.0)

55 (93.2)

  1. Abbreviations: DN dysplastic nevus, n number