Fig. 4

The effect of miR-15a-5p on the viability and apoptosis of hippocampal neuron. a. Transfection of miR-15a-5p mimic lead to a remarkable increase in the expression level of miR-15a-5p. b. The viability of hippocampal cells treated in the magnesium-free medium was significantly reduced which was reversed by miR-15a-5p mimic transfection. c. The cell apoptosis of hippocampal cells treated in the magnesium-free medium was significantly increased, overexpression of miR-15a-5p attenuated TLE-induced cell apoptosis. *** P < 0.001, compared with control group; ^###P < 0.001, compared with No Mg²⁺ group