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Table 1 Clinicopathological data of the studied bladder carcinoma cases

From: ROC-1, P21 and CAIX as markers of tumor aggressiveness in bladder carcinoma in Egyptian patients

VariablesCategoryNo. (%)
AgeMean ± SD62 ± 8.76
Range45–96
SexMale72 (90%)
Female8 (10%)
M:F8: 1
SizeMean ± SD4.64 ± 2
Range1–10
Muscularis propria invasion
Urothelial carcinoma
Non-invasive30 (37.50%)
Invasive50 (62.50%)
Histologic TypeInfiltrating UC58 (72.5%)
UC with divergent differentiation (squamous or glandular)14 (17.5%)
Squamous cell carcinoma5 (6.25%)
Small cell neuroendocrine3 (3.75%)
Gradingofurothelial carcinomaLow14 (18.7%)
High61 (81.3%)
Grading of squamous cell carcinomaModerately differentiated4 (80%)
Poorly differentiated1 (20%)
BilharziasisPresent26 (32.50%)
Absent54 (67.5%)
NecrosisPresent20 (25%)
Absent60 (75%)
Lymph-vascular invasionPresent14 (17.50%)
Absent66 (82.50%)
Perineural invasionPresent8 (10.00%)
Absent72 (90.00%)
Stromal reactionDesmoplastic60 (75.00%)
Inflammatory20 (25.00%)
Lymph node stage (TNM)N025 (50.00%)
N19 (18.00%)
N216 (32.00%)
Mitotic indexlow index50 (62.25%)
High index30 (37.50%)
Apoptotic indexlow index44 (55.00%)
High index36 (45.00%)
  1. SD Standard deviation, No number, UC Urothelial carcinoma