Table 1 Clinicopathological data of the studied bladder carcinoma cases
From: ROC-1, P21 and CAIX as markers of tumor aggressiveness in bladder carcinoma in Egyptian patients
Variables | Category | No. (%) |
|---|---|---|
Age | Mean ± SD | 62 ± 8.76 |
Range | 45–96 | |
Sex | Male | 72 (90%) |
Female | 8 (10%) | |
M:F | 8: 1 | |
Size | Mean ± SD | 4.64 ± 2 |
Range | 1–10 | |
Muscularis propria invasion Urothelial carcinoma | Non-invasive | 30 (37.50%) |
Invasive | 50 (62.50%) | |
Histologic Type | Infiltrating UC | 58 (72.5%) |
UC with divergent differentiation (squamous or glandular) | 14 (17.5%) | |
Squamous cell carcinoma | 5 (6.25%) | |
Small cell neuroendocrine | 3 (3.75%) | |
Gradingofurothelial carcinoma | Low | 14 (18.7%) |
High | 61 (81.3%) | |
Grading of squamous cell carcinoma | Moderately differentiated | 4 (80%) |
Poorly differentiated | 1 (20%) | |
Bilharziasis | Present | 26 (32.50%) |
Absent | 54 (67.5%) | |
Necrosis | Present | 20 (25%) |
Absent | 60 (75%) | |
Lymph-vascular invasion | Present | 14 (17.50%) |
Absent | 66 (82.50%) | |
Perineural invasion | Present | 8 (10.00%) |
Absent | 72 (90.00%) | |
Stromal reaction | Desmoplastic | 60 (75.00%) |
Inflammatory | 20 (25.00%) | |
Lymph node stage (TNM) | N0 | 25 (50.00%) |
N1 | 9 (18.00%) | |
N2 | 16 (32.00%) | |
Mitotic index | low index | 50 (62.25%) |
High index | 30 (37.50%) | |
Apoptotic index | low index | 44 (55.00%) |
High index | 36 (45.00%) |