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Table 2 Immunohistochemical profile of the studied ROC-1,CAIX and p21 in the studied bladder carcinoma cases

From: ROC-1, P21 and CAIX as markers of tumor aggressiveness in bladder carcinoma in Egyptian patients

VariablesMalignant cases (No = 80)
No (%)
ROC1 expression
 Positive72 (90%)
 Negative8 (10%)
 No = 72
RCO1 subcellular localization
 Cytoplamic24 (33.3%)
 Nucleo-cytoplasmic48 (66.7%)
ROC-1 intensity
 Predominant strong18 (25.0%)
 Predominant moderate30 (41.7%)
 Predominant mild24 (33.3%)
ROC1 H.score
 Low expression37 (51.4%)
 High expression35 (48.6%)
CAX expression
 Positive49 (92.5%)
 Negative31 (73.8%)
 No = 49
CAX subcellular localization
 Cytoplamic44 (89.7%)
 Nucleo-cytoplasmic5 (10.2%)
CAIX intensity
 Predominant strong 
 Predominant moderate 
 Predominant mild 
CAX H-score
 Low expression31 (63.3%)
 High expression18 (36.7%)
P21 expression
 Positive67 (83.75%)
  Negative13 (16.25%)
 No = 67
P21 subcellular localization
 Cytoplamic55 (82.1%)
 Nucleo-cytoplasmic12 (17.9%)
P21 intensity
 Predominant strong 
 Predominant moderate 
 Predominant mild 
P21 H-score
 Low expression34 (50.7%)
 High expression49 (92.5%)
  1. No number