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Table 6 Univariate survival analysis for studied bladder carcinoma cases

From: ROC-1, P21 and CAIX as markers of tumor aggressiveness in bladder carcinoma in Egyptian patients

VariableOverall survival (months)
Mean survival timeSELog rankP-value
Gender
 Male42.4172.3230.0090.926
 Female45.4294.508
Age (years)
 ≤ 6043.1202.9540.0240.877
 > 6042.2092.979
Size of mass
 Absent44.2583.5510.00.982
 Present42.2102.472
Diagnosis
 TCC42.9862.1390.0210.886
 Squamous ca43.8008.941
Grade
 Poorly diff30.00.01.7260.422
 Moderate differ.47.25010.872
 High42.9862.139
Bilharsiasis
 Absent44.6322.6542.2710.132
 Present39.4383.244
Necrosis
 Absent43.6152.4750.0470.829
 Present40.8573.787
LVI
 Absent42.8282.3540.0660.798
 Present42.7784.558
PNI
 Absent43.5372.2031.2110.271
 Present37.8336.263
Stroma
 Inflammatory41.7693.5300.2320.630
 Desmoplastic43.2522.559
Tumor stage
 T144.2583.5511.9220.589
 T243.1293.213
 T339.0543.823
 T452.33311.681
Ms invaion
 Absent44.2583.5510.00.982
 Present42.2102.472
Node
 Absent41.8482.3220.9880.320
 Present44.3224.061  
Reactivity (ROC-1 Immunohistochemistry)
 Negative59.00.01.4540.228
 Positive42.1002.095
Pattern (ROC-1 Immunohistochemistry)
 Negative59.00.02.4150.299
 Cytoplasmic40.1343.038
 Nuclear/cytopl42.9402.723
H score (ROC-1 Immunohistochemistry)
 Low median (< 90)43.9042.9040.0440.834
 High median (> 90)41.9472.987
IRS (ROC-1 Immunohistochemistry)
 Low43.5192.4541.3230.250
 High40.7003.950
Reactivity (CAIX Immunohistochemstry
 Negative45.9483.1491.0770.299
 Positive40.8562.703
Pattern (CAIX Immunohistochemstry
 Negative45.9483.1491.0770.299
 Cytoplasmic40.8562.703
H score (CAIX Immunohistochemstry
 Low median (< 90)43.3423.6283.4980.061
 High median (> 90)36.5003.591
  1. No comparison analysis was performed for urothelial carcinoma and squamous cell carcinoma grades because the factor variable had only one value
  2. CI Confidence interval