Fig. 2
From: Expression of RSK4, CD44 and MMP-9 is upregulated and positively correlated in metastatic ccRCC
Positive expression of MMP-9 predicts poor outcome of metastatic ccRCCs patients. The Kaplan-Meier survival curve showed the association between MMP-9 positive and negative expression in 29 metastatic ccRCCs patients (P = 0.038), and similar association was observed for WHO/ISUP nucleolar grade 1–2 and 3–4 (P = 0.018). However, RSK4, CD44, age, gender and metastatic sites were not statistically significant (P > 0.05). Figure a-f, blue line represents positive while red line represents negative. In figure g, blue, green, red, purple, and yellow represent bone, lung, brain, soft tissues and other metastatic sites, respectively. (a) RSK4; (b) CD44; (c) MMP-9; (d) age; (e) gender; (f) WHO/ISUP nucleolar grade; (g) metastatic sites