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Table 1 Comparison of clinicopathologic characteristics according to the Gli1 expression in GA

From: Gli1 regulates stemness characteristics in gastric adenocarcinoma

Variable

N

Gli1(−)n (%)

Gli1(+)n (%)

χ2

R

P

Age (years)

   

1.448

0.093

0.229

 < 65

109

32(29.4)

77(70.6)

   

 ≥ 65

60

13(21.7)

47(78.3)

   

Sex

   

1.347

0.089

0.246

 Male

106

25(23.6)

81(76.4)

   

 Female

63

20(31.7)

43(68.3)

   

Tumor size (cm)

   

0.759

0.065

0.384

 < 4.5

63

19(30.2)

44(69.8)

   

 ≥ 4.5

106

26(24.5)

80(75.5)

   

Tumor grade

   

15.771

0.049

0.001*

 Well

31

14(45.2)

17(54.8)

   

 Moderate

66

11(16.7)

55(83.3)

   

 Poor

72

20(27.8)

52(72.2)

   

Tumor location

   

1.943

0.024

0.584

 Antrum

93

23(24.7)

70(75.2)

   

 Cardia

3

0(0)

3(100.0)

   

 Body

63

20(31.7)

43(68.3)

   

 Mix

10

2(20.0)

8(80.0)

   

pT stage

   

9.034

0.218

0.029*

 1

35

16(45.7)

19(54.3)

   

 2

38

11(28.9)

27(71.1)

   

 3

92

17(18.5)

75(81.5)

   

 4

4

1(25.0)

3(75.0)

   

Lymph node metastasis

   

1.949

0.105

0.163

 Negative

144

41(28.5)

103(71.5)

   

 Positive

25

4(16.0)

21(84.0)

   

Distant metastasis

   

7.403

0.208

0.007*

 Negative

151

45(29.8)

106(70.2)

   

 Positive

18

0(0)

18(100.0)

   

Clinical stage

   

12.799

0.262

0.005*

 1

44

18(40.9)

26(59.1)

   

 2

34

11(32.4)

23(67.6)

   

 3

73

16(21.9)

57(78.1)

   

 4

18

0(0)

18(100.0)

   

Gross type

   

5.365

0.177

0.021*

 Early gastric cancer

37

16(43.2)

21(56.8)

   

 Advanced gastric cancer

132

29(22.0)

103(78.0)

   

Histological type

   

0.389

0.032

0.823

 Intestinal

91

26(28.6)

65(71.4)

   

 Diffuse

70

17(24.3)

53(75.7)

   

 Mix

8

2(25.0)

6(75.0)

   

Survival

   

23.883

0.375

< 0.001*

 Die

78

7(9.0)

71(91.0)

   

 Alive

91

38(41.8)

53(58.2)

   
  1. *Statistically significant findings