Table 2 Immunohistochemical profile of perianal Paget’s disease
From: Perianal Paget’s disease: a clinicopathological and immunohistochemical study of 13 cases
Primary | Secondary | P value | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ||
Cytokeratin 7 | + | + | + | + | + | – | + | + (F) | – | + | ND | + | – | NS |
Cytokeratin 20 | – | – | + | + (F) | + | + | – | + | + | + | ND | + | + | NS |
CDX2 | – | – | ND | – | + | + | ND | + | + | + | ND | + | + | 0.008 |
MUC1 | + | + | ND | + | + | – | ND | – | ND | ND | ND | + | – | NS |
MUC2 | + | + | ND | + (F) | + | + | ND | + | ND | ND | ND | + | + | NS |
CEA | + | – | ND | + (F) | ND | + | + | + | ND | + | ND | ND | + | NS |
GCDFP-15 | + (F) | + | ND | + (F) | – | – | ND | – | ND | – | ND | – | – | 0.012 |
P40 | – | – | ND | – | – | – | ND | – | ND | ND | ND | ND | – | NS |
Mucicarmine | + | + | + | + | ND | + | + | + | ND | ND | ND | ND | + | NS |
GATA3 | + | + | ND | + | ND | – | ND | – | ND | ND | ND | – | + | NS |