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Table 1 Clinicopathological data of diffuse large B-cell lymphoma (DLBCL) complicating ulcerative colitis published in English literature from 2001 to 2019

From: A case of iatrogenic immunodeficiency-associated colonic lymphoma complicating ulcerative colitis

Authors, year

Age/Sex

Ulcerative colitis

Immunosuppressant treatment

Iatrogenic immunodeficiency-associated lymphoproliferative disorders

Outcome

Site

Duration (month)

Immuno-suppressant

Duration (month)

Type

Site

Mass

EBV

perforation

Tan, et al., 2001 [4]

36/M

Left-side

84

AZA

32

DLBCL

Rectum

+

N/A

N/A

Dead (due to renal insufficiency by the disease progression)

Khan, et al., 2001 [5]

55/M

Pancolic

300

None

None

LCL, B-cell lineage

Rectum

N/A

N/A

N/A

Remission

Watanabe, et al., 2003 [6]

42/F

Left-side

120

None

None

DLBCL

Colon

+

N/A

N/A

Dead (due to MRSA pneumonia after the transplant)

Schwartz, et al., 2006 [7]

29/M

Pancolic

48

6MP, IFX, CYA

24

DLBCL

Ileal pouch

+

+

N/A

Remission

Shibahara, et al., 2006 [8]

33/M

Pancolic

108

AZA, CYA

48

DLBCL

Rectum

+

N/A

N/A

Remission

Van Hauwaert, et al., 2010 [9]

20/M

N/A

N/A

AZA, IFX

60

DLBCL

Rectum

+

N/A

N/A

Khan, et al., 2012 [10]

59/M

N/A

132

None

None

DLBCL

Rectum

+

N/A

+

N/A

Allen, et al., 2013 [1]

65/M

Left-side

60

AZA, 6MP, IFX

60

DLBCL

Colon

+

+

+

N/A

Hiyama, et al., 2014 [11]

69/M

Left-side

42

AZA

24

DLBCL

Rectum

-;

Ulcer

+

+

Dead (due to DIC secondary to sepsis)

Chang, et al. 2016 [3]

73/M

Pancolic

N/A

MTX

Several years

DLBCL

Colon

+

+

N/A

N/A

Our case

68/M

Pancolic

26

AZA, IFX

6

DLBCL

Colon

+

+

+

Remission

  1. M male, F female, AZA azathioprine, 6MP 6-mercaptopurine, IFX infliximab, CYA cyclosporine A, MTX methotrexate, LCL large cell lymphoma, LN lymph node, EBV Epstein-Barr virus, N/A not available, MRSA methicillin-resistant Staphylococcus aureus, DIC disseminated intravascular coagulation syndrome