From: High tumor mutation burden is associated with DNA damage repair gene mutation in breast carcinomas
Pathways | NER | MMR | FA | HR | Checkpoint | Others |
---|---|---|---|---|---|---|
Genes | ERCC2 | MLH1 | BRCA2 | BRCA1 | ATM | POLE |
 | ERCC3 | MSH2 | BRIP1 | MRE11A | ATR | MUTYH |
 | ERCC4 | MSH6 | FANCA | NBN | CHEK1 | PARP1 |
 | ERCC5 | PMS1 | FANCC | RAD50 | CHEK2 | RECQL4 |
 |  | PMS2 | PALB2 | RAD51 | MDC1 |  |
 |  |  | RAD51C | RAD51B |  |  |
 |  |  | BLM | RAD51D |  |  |
 |  |  |  | RAD52 |  |  |
 |  |  |  | RAD54L |  |  |