From: High tumor mutation burden is associated with DNA damage repair gene mutation in breast carcinomas
Case | Age (yr) | Phenotype | ER | PR | HER2 | Gene mutations | TMB (#/MB) |
---|---|---|---|---|---|---|---|
1 | 70 | Lobular | 95 | 0 | Negative | PIK3CA,PTEN, ARID1A, CDH1, CHD4, FAM123B, SMAD4, TP53 | 33 |
2 | 50 | Ductal, NOS | 90 | 0 | Negative | MAGI2*, PIK3C2B, PIK3CA, PIK3R1, SPEN, TP53 | 61 |
3 | 57 | Ductal, NOS | 99 | 0 | Negative | ERBB4, ESR1, GATA3, IGF1R,MAGI2**, PAX5 | 20 |