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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Dysregulation of miR-3607 predicts prognosis of hepatocellular carcinoma and regulates tumor cell proliferation, migration and invasion

Fig. 3

Effects of miR-3607 on cell proliferation, migration and invasion in Huh7 and SNU449 cell lines. a. Expression of miR-3607 was upregulated by the miR-3607 mimic and downregulated by the miR-3607 inhibitor (***P < 0.001). b. Cell proliferation of Huh7 and SNU449 cells was enhanced by the knockdown of miR-3607, but was inhibited by the overexpression of miR-3607 (*P < 0.05, **P < 0.01). c and d. The upregulated miR-3607 expression in HCC cells led to suppressed cell migration (c) and invasion (d), whereas the downregulated miR-3607 expression led to the opposite migration and invasion results (**P < 0.01, ***P < 0.001)

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