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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Prognostic perspectives of PD-L1 combined with tumor-infiltrating lymphocytes, Epstein-Barr virus, and microsatellite instability in gastric carcinomas

Fig. 3

Representative features of each molecular group. a, c, e Hematoxylin and eosin-stained images of each group. a-b Epstein-Barr virus (EBV)-positive gastric carcinoma; b Black signals are detected in most tumor cell nuclei by in situ hybridization for EBV-encoded small RNAs. c-d Microsatellite instability (MSI)-high gastric carcinoma; d Microsatellites are recognized for five markers (BAT26, BAT25, D5S346, D17S250, and D2S123) by multiplex PCR, and are indicated with asterisks (*). e-g Conventional carcinoma (EBV-negative and non-MSI-high); hMLH1 f and hMSH2 g were retained in tumor cell nuclei

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Diagnostic Pathology

ISSN: 1746-1596

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