Table 3 Comparison of PD-L1 Expression and Tumor-Infiltrating Lymphocytes in Each Molecular Group
Conventional (n = 429) | EBV-positive (n = 32) | MSI-high (n = 53) | |
|---|---|---|---|
PD-L1 in tumor cells | *aP < 0.001 | *bP < 0.001 | |
Positive | 59 (14%) | 15 (47%) | 27 (51%) |
Negative | 370 (86%) | 17 (53%) | 26 (49%) |
PD-L1 in immune cells | *aP < 0.001 | ||
Positive | 186 (43%) | 30 (94%) | 28 (53%) |
Absent | 243 (57%) | 2 (6%) | 25 (47%) |
CD8+ | *aP < 0.001 | *bP < 0.001 | |
High | 189 (44%) | 30 (94%) | 38 (72%) |
Low | 240 (56%) | 2 (6%) | 15 (28%) |
FOXP3+ | *aP = 0.036 | ||
High | 199 (46%) | 21 (66%) | 20 (38%) |
Low | 230 (54%) | 11 (34%) | 33 (62%) |
PD-1+ | *aP < 0.001 | ||
High | 142 (33%) | 23 (72%) | 16 (30%) |
Low | 287 (67%) | 9 (28%) | 37 (70%) |