Skip to main content

Table 3 Microscopy findings

From: Clinicopathologic features of infection-related glomerulonephritis with IgA deposits: a French Nationwide study

Variables

n = 27

Histologic features

No. of glomeruli (mean ± SD (range))

15 ± 9 (3–46)

Globally sclerotic glomeruli (mean ± SD (range))

2 ± 2 (0–8)

Mesangial hypercellularity (n (%))

24 (88.9)

Endocapillary proliferation (n (%))

24 (88.9)

  Segmental (n (%))/Global (n (%))

9 (33.3)/15 (55.6)

  Focal (n (%))/Diffuse (n (%))

10 (37.0)/14 (51.9)

Exudative endocapillary proliferation (n (%))

22 (81.4)

   < 5 neutrophils per glomerulus (n (%))/≥5 neutrophils per glomerulus (n (%))

15 (55.5)/7 (25.9)

Membranoproliferative pattern (n (%))

9 (33.3)

Crescentic proliferation (n (%))

10 (37.0)

Cellular (n(%))/Fibrocellular (n(%))/Fibrous (n(%))

7 (25.9%)/5 (18.5%)/0

Fibrinoid necrosis (n (%))

3 (11.1)

Deposits (n (%))

16 (59.2)

  Subepithelial humps (n (%))/Intramembranous (n (%))

13 (48.1)/3 (11.1)

Interstitial fibrosis and tubular atrophy (n (%))

23 (85.1)

  Mild (n (%))/Moderate (n (%))/Severe (n (%))

12 (44.4)/5 (18.5)/6 (22.2)

Interstitial inflammation (n (%))

21 (77.8)

  Mild (n (%))/Moderate (n (%))/Severe (n (%))

16 (59.3)/5 (18.5)/0

Acute tubular injury (n (%))

23 (85.1)

  Mild (n (%))/Moderate (n (%))/Severe (n (%))

8 (29.6)/8 (29.6)/7 (25.9)

Red blood cells casts (n (%))

18 (66.7)

Arteriosclerosis (n (%))

24 (88.9)

  Mild (n (%))/Moderate (n (%))/Severe (n (%))

4 (14.8)/16 (59.3)/4 (14.8)

Histologic pattern

Acute (n (%))

7 (25.9)

Subacute (n (%))

17 (63.0)

Resolving (n (%))

3 (11.1)

  1. Abbreviations: SD standard deviation