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Table 5 Outcome and prognostic factors (25 patients)

From: Clinicopathologic features of infection-related glomerulonephritis with IgA deposits: a French Nationwide study

 

eGFR > 60 mL/min/1.73m2 a

PRD b

ESRD c

P values

No. of patients

7

14

4

 

% of patients

28

56

16

 

Age, year

61

64

68

0.8

Median follow-up, months

8.3

16.5

21.6

0.3

Mean eGFR, ml/min/1.73m2

  At biopsy

28.9

20.9

17.5

0.6

  Follow-up

84.6

37.5

< 0.001

Mean proteinuria at biopsy, g/day

3.5

5.5

6.5

0.2

Corticosteroids, % of patients

0

64

25

0.01

Median infection-renal injury delay, days (IQR)

13 (8.5–36)

23 (17.8–69)

13 (10–47.3)

0.3

Histologic pattern (acute/subacute/resolving, %)

29/57/14

29/64/7

50/25/25

0.1

Global glomerulosclerosis, % of glomeruli

13

18

44

0.2

Crescentic proliferation, % of glomeruli

4

6

5

0.9

Interstitial inflammation score, mean

0.9

0.9

1.5

0.2

Acute tubular injury score, mean

1.6

1.8

1.75

0.8

IF/TA score, mean

0.9

1.6

2.5

0.02

Arteriosclerosis, mean

2

1.8

2

0.6

  1. Abbreviations: eGFR estimated glomerular filtration rate, ESRD end-stage renal disease, IF/TA interstitial fibrosis with tubular atrophy, IQR interquartile ranges, PRD persistent renal disease (eGFR< 60 ml/min/1.73m2)
  2. aOne patient with eGFR> 60 died; bOne patient with PRD died; cTwo patients with ESRD died