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Table 5 Outcome and prognostic factors (25 patients)

From: Clinicopathologic features of infection-related glomerulonephritis with IgA deposits: a French Nationwide study

 eGFR > 60 mL/min/1.73m2 aPRD bESRD cP values
No. of patients7144 
% of patients285616 
Age, year6164680.8
Median follow-up, months8.316.521.60.3
Mean eGFR, ml/min/1.73m2
  At biopsy28.920.917.50.6
  Follow-up84.637.5< 0.001
Mean proteinuria at biopsy, g/day3.55.56.50.2
Corticosteroids, % of patients064250.01
Median infection-renal injury delay, days (IQR)13 (8.5–36)23 (17.8–69)13 (10–47.3)0.3
Histologic pattern (acute/subacute/resolving, %)29/57/1429/64/750/25/250.1
Global glomerulosclerosis, % of glomeruli1318440.2
Crescentic proliferation, % of glomeruli4650.9
Interstitial inflammation score, mean0.90.91.50.2
Acute tubular injury score, mean1.61.81.750.8
IF/TA score, mean0.91.62.50.02
Arteriosclerosis, mean21.820.6
  1. Abbreviations: eGFR estimated glomerular filtration rate, ESRD end-stage renal disease, IF/TA interstitial fibrosis with tubular atrophy, IQR interquartile ranges, PRD persistent renal disease (eGFR< 60 ml/min/1.73m2)
  2. aOne patient with eGFR> 60 died; bOne patient with PRD died; cTwo patients with ESRD died