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Table 1 CK20, AMACR, and p53 staining in Intradepartmental Consensus Urothelial Lesions

From: CK20 versus AMACR and p53 immunostains in evaluation of Urothelial Carcinoma in Situ and Reactive Atypia

  CK20 ProportionCK20 IntensityAMACR ProportionAMACR Intensityp53 Patterna
 N (%)±+0+1+2+±+0+1+2+Wild typeMutantEquivocal
Reactive1513 (87)1 (7)1 (7)13 (87)1 (7)1 (7)15 (100)0015 (100)0012 (80)03 (20)
CIS151 (7)4 (27)10 (67)1 (7)4 (27)10 (67)3 (20)5 (33)7 (47)3 (20)8 (53%)4 (27)1 (7)9 (60)5 (33)
  1. Abbreviations: CK20 cytokeratin 20, AMACR alpha-methylacyl-CoA racemase;
  2. Staining Proportion: -, negative; ±, patchy; +, diffuse
  3. Staining Intensity: 0+ negative; 1+ weak; 2+ strong
  4. a Please see Methods for description of scoring pattern