Skip to main content

Table 3 Multivariate Cox regression analysis for overall survival and relapse-free survival

From: Expression of FAM83H and ZNF16 are associated with shorter survival of patients with gallbladder carcinoma

Characteristics

OS

p

RFS

p

HR (95% CI)

HR (95% CI)

Age, y ≥ 65 (vs. <  65)

3.698 (2.194–6.233)

<  0.001

3.484 (2.085–5.824)

<  0.001

TNM stage

 I

1

<  0.001

1

<  0.001

 II

2.304 (1.021–5.197)

0.044

2.473 (1.101–5.556)

0.028

 III

6.168 (2.715–14.011)

<  0.001

5.819 (2.554–13.259)

<  0.001

 IV

25.342 (8.985–71.472)

<  0.001

23.060 (8.258–64.396)

<  0.001

Nuclear FAM83H, positive (vs. negative)

2.094 (1.243–3.525)

0.005

2.108 (1.260–3.527)

0.005

  1. Abbreviations: OS overall survival, RFS relapse-free survival, HR hazard ratio, 95% CI 95% confidence interval. Variables considered in the multivariate analysis were age, preoperative serum level of CA19–9, tumor stage, T category of tumor stage, lymph node metastasis, distant metastasis, lymphovascular invasion, histologic type, histologic grade, and the expression of nuclear FAM83H, cytoplasmic FAM83H, nuclear ZNF16, and cytoplasmic ZNF16