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Table 3 Multivariate Cox regression analysis for overall survival and relapse-free survival

From: Expression of FAM83H and ZNF16 are associated with shorter survival of patients with gallbladder carcinoma

CharacteristicsOSpRFSp
HR (95% CI)HR (95% CI)
Age, y ≥ 65 (vs. <  65)3.698 (2.194–6.233)<  0.0013.484 (2.085–5.824)<  0.001
TNM stage
 I1<  0.0011<  0.001
 II2.304 (1.021–5.197)0.0442.473 (1.101–5.556)0.028
 III6.168 (2.715–14.011)<  0.0015.819 (2.554–13.259)<  0.001
 IV25.342 (8.985–71.472)<  0.00123.060 (8.258–64.396)<  0.001
Nuclear FAM83H, positive (vs. negative)2.094 (1.243–3.525)0.0052.108 (1.260–3.527)0.005
  1. Abbreviations: OS overall survival, RFS relapse-free survival, HR hazard ratio, 95% CI 95% confidence interval. Variables considered in the multivariate analysis were age, preoperative serum level of CA19–9, tumor stage, T category of tumor stage, lymph node metastasis, distant metastasis, lymphovascular invasion, histologic type, histologic grade, and the expression of nuclear FAM83H, cytoplasmic FAM83H, nuclear ZNF16, and cytoplasmic ZNF16