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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Angiogenesis in mammary Paget disease: histopathological analyses of blood vessel density and angiogenic factors

Fig. 1

A schematic illustration of the “nipple area” defined in this study. The nipple area (shaded with oblique lines) was defined as follows: the lateral borders were defined as the lateral borders of the nipple, the upper border as the basement membrane of the epidermis, and the lower border as the border between the collagenous tissue of the dermis and subcutaneous fatty tissue. The black circles represent CD34-positive vessel structures. The ratio of the blood vessel lumen area to nipple area was defined as follows: (the summed area of all CD34-positive vessel structures / the nipple area) × 100

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