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Fig. 5 | Diagnostic Pathology

Fig. 5

From: Angiogenesis in mammary Paget disease: histopathological analyses of blood vessel density and angiogenic factors

Fig. 5

Immunohistochemical expression of basic fibroblast growth factor (bFGF) (a-c, × 200) and vascular endothelial growth factor A (VEGFA) (d-f, × 200). In control (a) and dermatitis (b) tissues, bFGF expression is absent in non-neoplastic epithelium and weak in the endothelium of the dermis. In Paget disease tissues (c), immunohistochemical bFGF expression is diffuse in the cytoplasm of Paget cells. VEGFA cytoplasmic expression is weak to moderate in non-neoplastic epithelium such as epidermis and sebaceous glands in the control (d) and dermatitis (e) groups, and weak to strong in Paget cells of the Paget disease group (f)

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Diagnostic Pathology

ISSN: 1746-1596

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