Table 2 Histopathologic, immunohistochemical and FISH findings of PI-FL and control cases with reactive lymphoid hyperplasia
Parameters | PI-FL (n = 21) | Control (n = 17) |
|---|---|---|
Features of the follicles | ||
Polarity | Lost | Preserved |
Cellular components | Mainly centrocytes | Mixed populations |
Tingible body macrophages | Absent | Present |
Histologic grade | ||
1/2 | 19 (91%)/ 2 (10%) | NA |
Immunohistochemistry | ||
CD10 expression | 21 (100%) | |
BCL6 expression | 21 (100%) | |
BCL2 expression | 21 (100%) | |
FDC pattern | Tight meshwork | |
Duodenal | 14 (67%; 11 duodenum, 1 ileum and 2 colon) | |
Nodal | 6 (29%; 4 ileocecum and 2 jejunum) | |
Mixed duodenal and nodal | 1 (5%) | |
FISH IGH/BCL2 | ||
Positive/ Negative/ Failed/ Not tested | 17/1/2/1 | |