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Fig. 4 | Diagnostic Pathology

Fig. 4

From: A novel collision tumour of myofibroblastoma and low-grade adenosquamous carcinoma in breast

Fig. 4

Immunohistochemistry. a. Ki-67 showed very low proliferating index. b. CD34 was strongly and diffusely positive in the spindle cells. c and d. CK and CK5/6 were negative in the spindle cells but strongly positive in the epithelial elements, which confirmed the characteristics and displayed the distorted outlines. e and f. ER and PR were diffusely positive in the spindle cells and negative in the epithelial elements. g and h. SMA and desmin were diffusely positive in the spindle cells, which suggested myogenic differentiation. SMA was positive patchily and desmin was negative in the outer-layer of epithelial elements. i and j. P63 was positive in the outer-layer of the tubules just as that in the normal glands, and in nearly all the cells of the solid nests

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