Table 1 Immunohistochemical patterns of MMR protein loss in colorectal and endometrial cancer
From: Next generation sequencing to decipher concurrent loss of PMS2 and MSH6 in colorectal cancer
MLH1/PMS2 | MSH2/MSH6 | PMS2 | MSH6 | 4 MMR | MLH1/PMS2/MSH6 | PMS2/MSH6 | Total | |
|---|---|---|---|---|---|---|---|---|
CRC | 85 / 78.7% | 11 / 10.2% | 3 / 2.8% | 5 / 4.6% | 1 / 0.9% | 1 / 0.9% | 2 / 1.9% | 108 / 100% |
EC | 27 / 77.1% | 3 / 8.6% | 0 / 0% | 5 / 14.3% | 0 / 0% | 0 / 0% | 0% | 35 / 100% |