Fig. 1From: miR-541 serves as a prognostic biomarker of osteosarcoma and its regulatory effect on tumor cell proliferation, migration and invasion by targeting TGIF2miR-541 was downregulated in human OS tissues and cell lines. a The expression of miR-541 was significantly decreased in OS tissues compared with adjacent normal tissues (***P < 0.001). b The expression of miR-541 was reduced in patients with poor differentiation (***P < 0.001). c The expression of miR-541 was downregulated in patients with advanced Enneking stage compared with those with early stage (***P < 0.001). (D) The expression of miR-541 was significantly decreased in OS cell lines compared with normal cells (***P < 0.001)Back to article page