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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Malakoplakia of the gastrointestinal tract: clinicopathologic analysis of 23 cases

Fig. 2

CD68 immunostain highlights the histiocytes in malakoplakia. CD68 immunostain 200x magnification (a). Von Kossa special stain highlights the calcified and lamellated Michaelis-Gutman bodies. Von Kossa special stain 400x magnification (b). Since immunocompromised patients are at risk for malakoplakia, concomitant cytomegalovirus infection (arrow) can be seen. H&E 400x magnification (c). CMV immunostain highlights intra-nuclear viral inclusions. CMV immunostain 400x magnification (d). Entamoeba histolytica is a protozoal parasite (arrow) with foamy cytoplasm, phagocytized red blood cell inclusions, and eccentrically located nuclei. These microorganisms were seen in a patient with malakoplakia. H&E 400x magnification (e)

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