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Table 1 Clinicopathologic findings for crawling-type adenocarcinomas (CRAs) and conventional differentiated adenocarcinomas (CDAs)

From: Analysis of clinicopathological and molecular features of crawling-type gastric adenocarcinoma

  CRA (%) CDA (%) P-value
Total (lesions) 51 126  
Age (years) (median) [range] 71 [39–86] 73 [45–91] 0.048
Gender    0.56
 Male 35 (68.6) 92 (73.0)  
 Female 16 (31.4) 34 (27.0)  
Location    <  0.01
 Upper 7 (13.7) 24 (19.0)  
 Middle 32 (62.8)* 46 (36.5)*  
 Lower 12 (23.5)* 56 (44.4)*  
Macroscopic type    <  0.01
 Depressed type 37 (72.5) 46 (36.5)  
 Elevated, flat or mixed type 14 (27.5) 80 (63.5)
Tumor size (mm) (median) [range] 28 [8–150] 20 [7–103] <  0.01
Predominant histological component    <  0.01
 Well-differentiated adenocarcinoma 8 (15.7)** 100 (79.3)**  
 Moderately differentiated adenocarcinoma 41 (80.4)** 19 (15.1)**  
 Papillary adenocarcinoma 0 (0.0) 7 (5.6)  
 Poorly differentiated adenocarcinoma 2 (3.9) 0 (0.0)  
Histological subtype    <  0.01
 Pure differentiated adenocarcinoma 27 (52.9) 109 (86.5)  
 Mixed differentiated and poorly differentiated adenocarcinoma 24 (47.1) 17 (13.5)  
Tumor extent    0.68
 Mucosa [pTis/pT1a] 34 [0/34] (66.7) 88 [62/26] (69.8)  
 Submucosa 17 (33.3) 38 (30.2)  
Ulcer or ulcer scar    0.29
 Present 12 (23.5) 21 (16.7)  
 Absent 39 (76.5) 105 (83.3)  
Lymphatic involvement    0.90
 Present 6 (11.8) 14 (11.1)  
 Absent 45 (88.2) 112 (88.9)  
Vascular involvement    0.96
 Present 2 (3.9) 3 (2.4)  
 Absent 49 (96.1) 123 (97.6)  
Horizontal margin    0.08
 Positive 8 (15.7) 9 (7.1)  
 Negative 43 (84.3) 117 (92.9)  
Vertical margin
 Positive 4 (7.8) 14 (11.1) 0.71
 Negative 47 (92.2) 112 (88.9)  
  1. P-values < 0.05 are in bold text
  2. *, p <  0.05; **, p <  0.01