Table 1 Clinicopathologic findings for crawling-type adenocarcinomas (CRAs) and conventional differentiated adenocarcinomas (CDAs)
From: Analysis of clinicopathological and molecular features of crawling-type gastric adenocarcinoma
CRA (%) | CDA (%) | P-value | |
|---|---|---|---|
Total (lesions) | 51 | 126 | |
Age (years) (median) [range] | 71 [39–86] | 73 [45–91] | 0.048 |
Gender | 0.56 | ||
Male | 35 (68.6) | 92 (73.0) | |
Female | 16 (31.4) | 34 (27.0) | |
Location | < 0.01 | ||
Upper | 7 (13.7) | 24 (19.0) | |
Middle | 32 (62.8)* | 46 (36.5)* | |
Lower | 12 (23.5)* | 56 (44.4)* | |
Macroscopic type | < 0.01 | ||
Depressed type | 37 (72.5) | 46 (36.5) | |
Elevated, flat or mixed type | 14 (27.5) | 80 (63.5) | |
Tumor size (mm) (median) [range] | 28 [8–150] | 20 [7–103] | < 0.01 |
Predominant histological component | < 0.01 | ||
Well-differentiated adenocarcinoma | 8 (15.7)** | 100 (79.3)** | |
Moderately differentiated adenocarcinoma | 41 (80.4)** | 19 (15.1)** | |
Papillary adenocarcinoma | 0 (0.0) | 7 (5.6) | |
Poorly differentiated adenocarcinoma | 2 (3.9) | 0 (0.0) | |
Histological subtype | < 0.01 | ||
Pure differentiated adenocarcinoma | 27 (52.9) | 109 (86.5) | |
Mixed differentiated and poorly differentiated adenocarcinoma | 24 (47.1) | 17 (13.5) | |
Tumor extent | 0.68 | ||
Mucosa [pTis/pT1a] | 34 [0/34] (66.7) | 88 [62/26] (69.8) | |
Submucosa | 17 (33.3) | 38 (30.2) | |
Ulcer or ulcer scar | 0.29 | ||
Present | 12 (23.5) | 21 (16.7) | |
Absent | 39 (76.5) | 105 (83.3) | |
Lymphatic involvement | 0.90 | ||
Present | 6 (11.8) | 14 (11.1) | |
Absent | 45 (88.2) | 112 (88.9) | |
Vascular involvement | 0.96 | ||
Present | 2 (3.9) | 3 (2.4) | |
Absent | 49 (96.1) | 123 (97.6) | |
Horizontal margin | 0.08 | ||
Positive | 8 (15.7) | 9 (7.1) | |
Negative | 43 (84.3) | 117 (92.9) | |
Vertical margin | |||
Positive | 4 (7.8) | 14 (11.1) | 0.71 |
Negative | 47 (92.2) | 112 (88.9) | |