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Table 1 Clinical characteristics in 779 patients with GEP-NENs

From: Clinicopathological heterogeneity between primary and metastatic sites of gastroenteropancreatic neuroendocrine neoplasm

Variables

Total n = 779 (%)

Age at diagnosis (years)

55 (13–87)

Sex

 Male

460 (59.1)

 Female

319 (40.9)

Primary tumor site

 Pancreas

216 (27.7)

 Rectum

208 (26.7)

 Stomach

144 (18.5)

 Esophagus

44 (5.6)

 Duodenum

31 (4.0)

 Colon

29 (3.7)

 Gallbladder

18 (2.3)

 Appendix

11 (1.4)

 Small intestine

4 (0.5)

 Other sites

74 (9.5)

Tumor grade and type

 NET G1

313 (40.2)

 NET G2

144 (18.5)

 NET G3

4 (0.5)

 NEC

270 (34.7)

 MINEN

40 (5.1)

 Unknown

8 (1.0)

aCgA

 Positive

448 (57.5)

 Negative

221 (28.4)

 Unknown

110 (14.1)

aSyn

 Positive

665 (85.4)

 Negative

15 (1.9)

 Unknown

99 (12.7)

Metastasis

311 (39.9)

  1. Abbreviations: GEP-NENs gastroenteropancreatic neuroendocrine neoplasms, NET neuroendocrine tumors, NEC neuroendocrine carcinoma, MiNEN mixed neuroendocrine–non-neuroendocrine neoplasm, CgA chromogranin; Syn, synaptophysin. a The expression of CgA or Syn in primary site