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Table 1 Clinical characteristics in 779 patients with GEP-NENs

From: Clinicopathological heterogeneity between primary and metastatic sites of gastroenteropancreatic neuroendocrine neoplasm

Variables Total n = 779 (%)
Age at diagnosis (years) 55 (13–87)
Sex
 Male 460 (59.1)
 Female 319 (40.9)
Primary tumor site
 Pancreas 216 (27.7)
 Rectum 208 (26.7)
 Stomach 144 (18.5)
 Esophagus 44 (5.6)
 Duodenum 31 (4.0)
 Colon 29 (3.7)
 Gallbladder 18 (2.3)
 Appendix 11 (1.4)
 Small intestine 4 (0.5)
 Other sites 74 (9.5)
Tumor grade and type
 NET G1 313 (40.2)
 NET G2 144 (18.5)
 NET G3 4 (0.5)
 NEC 270 (34.7)
 MINEN 40 (5.1)
 Unknown 8 (1.0)
aCgA
 Positive 448 (57.5)
 Negative 221 (28.4)
 Unknown 110 (14.1)
aSyn
 Positive 665 (85.4)
 Negative 15 (1.9)
 Unknown 99 (12.7)
Metastasis 311 (39.9)
  1. Abbreviations: GEP-NENs gastroenteropancreatic neuroendocrine neoplasms, NET neuroendocrine tumors, NEC neuroendocrine carcinoma, MiNEN mixed neuroendocrine–non-neuroendocrine neoplasm, CgA chromogranin; Syn, synaptophysin. a The expression of CgA or Syn in primary site